OpenFederal grantOpen to for-profit businessesRFA-CA-27-021

Sustained Support for Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)

National Institutes of HealthCloses Oct 19, 2026(6 days left)$50,000 – $600,000

Does this fit your business?

This is an NIH/NCI program to keep existing, widely adopted cancer research informatics tools running, documented, and useful to their user communities, not to build new ones. It fits teams already operating a tool with demonstrated impact on cancer research. If you are starting a new product, have no established cancer research user base, or work outside health technology, do not bother.

Best for
Software teams with an existing, widely adopted cancer research tool, Universities and research institutions sustaining informatics resources, Nonprofits and small businesses maintaining cancer data platforms
Not for
Startups building a brand-new tool from scratch, Organizations with no existing informatics resource or user community, Retail, finance, or real estate businesses
Estimated fit by industry, best first
IndustryEstimated fit
Technology & SoftwareMatches your industry (technology, tech)
86
Strong Match
Social Services & NonprofitMatches your industry (community)
80
Strong Match
Healthcare & BiotechMatches your industry (clinical)
79
Strong Match
Education & TrainingCurrently accepting applications
72
Good Match
Agriculture & FarmingLimit: Nothing in this notice points to agriculture & farming
54
Possible Match
Arts & CultureLimit: Nothing in this notice points to arts & culture
54
Possible Match
Show all 15 industries
Estimated fit by industry, best first
IndustryEstimated fit
Construction & InfrastructureLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match
Energy & Clean TechLimit: Nothing in this notice points to energy & clean tech
54
Possible Match
Environment & ConservationLimit: Nothing in this notice points to environment & conservation
54
Possible Match
Finance & BankingLimit: Nothing in this notice points to finance & banking
54
Possible Match
Food & BeverageLimit: Nothing in this notice points to food & beverage
54
Possible Match
Housing & Real EstateLimit: Nothing in this notice points to housing & real estate
54
Possible Match
ManufacturingLimit: Nothing in this notice points to manufacturing
54
Possible Match
Retail & E-CommerceLimit: Nothing in this notice points to retail & e-commerce
54
Possible Match
Transportation & LogisticsLimit: Nothing in this notice points to transportation & logistics
54
Possible Match

These are our matcher’s estimates for a typical business in each industry. A real match depends on your size, your state and what you need the money for — check your own fit.

What this funds

Money can be used for
Operating support, Technical assistance, Training
Who can apply
Small businesses, For-profit companies, Nonprofits, State and local governments, Tribal governments and organizations, Colleges and universities, Other applicants (see eligibility)
Award range
$50,000 – $600,000

Questions about this grant

When is the application deadline?
Applications are due October 19, 2026.
How much funding can an applicant receive?
Awards range from $50,000 to $600,000, with total program funding of $1,800,000 and about 2 awards expected.
Who can apply for this grant?
Eligible applicants include small businesses, for-profit organizations, nonprofits (with and without 501(c)(3) status), private and public institutions of higher education, state, county, city and township governments, special district governments, independent school districts, public housing authorities, federally recognized tribal governments, tribal organizations, and others. Foreign organizations and foreign components of U.S. organizations are also eligible.
Can a sole proprietor or single-member LLC apply?
The facts do not say. The eligibility list names small businesses and for-profit organizations generally, but does not specifically address sole proprietors or single-member LLCs, so check Section III of the NOFO.
Can a nonprofit apply?
Yes. Both nonprofits having 501(c)(3) status and nonprofits without 501(c)(3) status (other than institutions of higher education) are listed as eligible.

Summary

NCI ITCR program funding to sustain and maintain existing, widely-adopted informatics tools and resources for cancer research. Eligible applicants include small businesses, for-profits, nonprofits, universities, state/local/tribal governments, and others; foreign entities may apply. Funds support sustained operations, user support, documentation, training, and community engagement.

About this grant

This Notice of Funding Opportunity (NOFO) solicits applications for the continued development and sustainment of high value informatics research resources to improve the acquisition, management, analysis, and dissemination of data and knowledge across the cancer research continuum including cancer biology, cancer treatment and diagnosis, early cancer detection, risk assessment and prevention, cancer control and epidemiology. As a component of the NCI's Informatics Technology for Cancer Research (ITCR) Program, this NOFO is focused on sustaining operations and maintaining and evolving the scientific relevance of existing, widely-adopted informatics tools and resources. This is in contrast to early-stage and advanced development efforts to generate these tools and resources that will be supported by companion ITCR NOFOs. The central mission of ITCR is to promote research-driven informatics technology across the development lifecycle to address priority needs in cancer research. In order to be successful, the application must provide clear justification for why the research resource should be maintained and how it has benefited and will continue to benefit the cancer research field. In addition, mechanisms for assessing and maximizing the value of the resource to researchers and supporting close engagement between the resource and the targeted research community should be described.This NOFO invites applications to support the sustained operations of informatics technology resources that support a wide range of cancer research, including discovery biology, population studies, as well as clinical and translational research. The emphasis is on sustaining resources that have had a demonstrated impact on cancer research. In addition, all projects proposed in response to this NOFO must involve the following general attributes:Evidence that the technology has had significant impact on cancer research to date and the sustainment plan will lead to the continued advancement of cancer researchRobust plans for supporting the end-user community including documentation, training, and other outreach activitiesClear processes for engaging end users to address emerging needs of the targeted research communities to ensure that the research resource maintains relevance to the research it supports

Who can apply

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/Foreign Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Topics and uses of funds

Topics

  • Health
  • Technology
  • Science

Program contact

National Institutes of Healthnciitcr@mail.nih.gov301-402-2541

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