OpenFederal grantOpen to for-profit businessesRFA-MH-27-180

Advancing Research on Empirically-Supported Interventions for Older Adults Living with Serious Mental Illness (SMI) (R01 Clinical Trial Optional)

National Institutes of HealthCloses Oct 15, 2026(2 days left)

Does this fit your business?

This is an NIH research grant (R01) for studies on improving mental health interventions for older adults with serious mental illness, run through settings like primary care, geriatric clinics, assisted living, and community centers. It is for organizations that can design and carry out rigorous research, not for those seeking funding to deliver services or cover operations. If your organization has no research capacity in mental health or aging, do not bother applying.

Best for
Research teams studying mental health care for older adults with serious mental illness, Universities, hospitals, and health systems running practice-relevant SMI research, Nonprofits and community organizations positioned as research partners in care settings, Small businesses and for-profits with research capabilities in behavioral health
Not for
Businesses with no research capability in mental health or aging, Organizations seeking funding to deliver services rather than study them, Applicants outside the research focus on older adults with serious mental illness
Estimated fit by industry, best first
IndustryEstimated fit
Healthcare & BiotechMatches your industry (health, clinical)
76
Strong Match
Environment & ConservationMatches your industry (sustainability)
65
Good Match
Education & TrainingMatches your industry (stem)
64
Good Match
Social Services & NonprofitMatches your industry (community)
64
Good Match
Arts & CultureLimit: Closes in 27 days
54
Possible Match
Energy & Clean TechLimit: Closes in 27 days
54
Possible Match
Show all 15 industries
Estimated fit by industry, best first
IndustryEstimated fit
Food & BeverageLimit: Closes in 27 days
54
Possible Match
Housing & Real EstateLimit: Closes in 27 days
54
Possible Match
ManufacturingLimit: Closes in 27 days
54
Possible Match
Technology & SoftwareLimit: Closes in 27 days
54
Possible Match
Transportation & LogisticsMatches your industry (transit)
54
Possible Match
Finance & BankingLimit: Closes in 27 days
53
Possible Match
Agriculture & FarmingLimit: Closes in 27 days
52
Possible Match
Retail & E-CommerceLimit: Closes in 27 days
52
Possible Match
Construction & InfrastructureLimit: Closes in 27 days
47
Possible Match

These are our matcher’s estimates for a typical business in each industry. A real match depends on your size, your state and what you need the money for — check your own fit.

What this funds

Money can be used for
Research
Who can apply
Small businesses, For-profit companies, Nonprofits, State and local governments, Tribal governments and organizations, Colleges and universities, Other applicants (see eligibility)

Questions about this grant

When is the application deadline?
Applications are due October 15, 2026.
How much funding can an applicant receive?
The facts do not say how much any single award will be. The total program funding is $3,000,000, with about 6 awards expected, so awards will likely be a fraction of that total, but no per-award amount is published.
Who can apply for this grant?
A wide range of organizations can apply, including small businesses, for-profit companies, nonprofits with or without 501(c)(3) status, public and private colleges and universities, state, county, city, township, and special district governments, federally recognized and other Native American tribal organizations, independent school districts, and public or Indian housing authorities. Foreign organizations and foreign components of U.S. organizations are also eligible. Check Section III of the NOFO for the full eligibility details.
Can a sole proprietor or single-member LLC apply?
The facts do not address sole proprietors or single-member LLCs specifically. Small businesses are listed as eligible, but you should check Section III of the NOFO to confirm whether your business structure qualifies.
Can a nonprofit apply?
Yes. Both nonprofits with 501(c)(3) status and nonprofits without 501(c)(3) status (other than institutions of higher education) are listed as eligible applicants.

Summary

NIH-funded R01 research grants to study and improve empirically-supported mental health interventions for older adults with serious mental illness. Eligible applicants include small businesses, for-profits, nonprofits, universities, state/local/tribal governments, school districts, housing authorities, and foreign organizations; clinical trials optional.

About this grant

The purpose of this notice of funding opportunity (NOFO) is to foster research that will inform and support the optimization, delivery, sustainability, and effectiveness of empirically-supported practices for addressing the mental health needs of older adults with serious mental illness (SMI). To this end, NIMH seeks applications that propose work that is focused on practice-relevant questions and conducted within and/or across settings where older adults with SMI are likely to be identified as needing care (e.g., primary care and geriatric specialty clinics, assisted living and long-term care facilities, and community centers). Applications may propose research related to adapting, optimizing, and implementing efficacious treatment and services interventions and strategies to improve clinical and functional outcomes among aging populations; examining mutable factors that impact fair and impartial mental health care access, utilization, quality, and outcomes and may serve as targets for intervention development for older adults with SMI; and developing and testing innovative treatment and service interventions that address barriers to accessing quality mental health care. Projects may also focus on systems-level factors and approaches for addressing SMI and improving access to evidence-based interventions in later life, such as evaluation of health system policies and practices, interventions that facilitate care transitions and continuity across settings, and strategies to improve care linkages and coordination across systems.

Who can apply

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Topics and uses of funds

Topics

  • Health
  • Mental health
  • Aging
  • Research

Program contact

National Institutes of HealthNIMH.DSIR.inquiries@mail.nih.gov301-402-2541

Related grants

Open opportunities funding similar work, from the same funder or in the same place.

All grantsGrants by stateGrants by industry