OpenFederal grantOpen to for-profit businessesRFA-AI-28-031

Centers for Structural Biology of HIV and Other Infectious Diseases (U54 Clinical Trial Not Allowed)

National Institutes of HealthCloses May 28, 2027(227 days left)Up to $3,500,000

Does this fit your business?

This is an NIH program funding multidisciplinary centers of structural biologists and microbiologists solving biological structures related to HIV and other infectious diseases, with awards up to $3.5 million and no clinical trials allowed. It fits research universities, nonprofits, and research-capable for-profits including small businesses that can join or lead such a center. Retail, finance, logistics, and other businesses with no biomedical research capability should not bother applying.

Best for
University and nonprofit research centers running structural biology or microbiology labs, Multidisciplinary consortia of structural biologists and microbiologists studying HIV or other infectious diseases, For-profit research organizations, including small businesses, that can contribute to a center without running clinical, Tribal, state, or local government entities supporting infectious-disease research infrastructure
Not for
Small businesses without structural biology or infectious-disease research capability, Organizations planning clinical trials or projects involving foreign subawards, Retail, finance, logistics, and other businesses outside biomedical research
Estimated fit by industry, best first
IndustryEstimated fit
Healthcare & BiotechMatches your industry (clinical)
77
Strong Match
Social Services & NonprofitMatches your industry (community)
71
Good Match
Agriculture & FarmingLimit: Nothing in this notice points to agriculture & farming
54
Possible Match
Arts & CultureLimit: Nothing in this notice points to arts & culture
54
Possible Match
Construction & InfrastructureLimit: Nothing in this notice points to construction & infrastructure
54
Possible Match
Education & TrainingLimit: Nothing in this notice points to education & training
54
Possible Match
Show all 15 industries
Estimated fit by industry, best first
IndustryEstimated fit
Energy & Clean TechLimit: Nothing in this notice points to energy & clean tech
54
Possible Match
Environment & ConservationLimit: Nothing in this notice points to environment & conservation
54
Possible Match
Finance & BankingLimit: Nothing in this notice points to finance & banking
54
Possible Match
Food & BeverageLimit: Nothing in this notice points to food & beverage
54
Possible Match
Housing & Real EstateLimit: Nothing in this notice points to housing & real estate
54
Possible Match
ManufacturingLimit: Nothing in this notice points to manufacturing
54
Possible Match
Retail & E-CommerceLimit: Nothing in this notice points to retail & e-commerce
54
Possible Match
Technology & SoftwareLimit: Nothing in this notice points to technology & software
54
Possible Match
Transportation & LogisticsLimit: Nothing in this notice points to transportation & logistics
53
Possible Match

These are our matcher’s estimates for a typical business in each industry. A real match depends on your size, your state and what you need the money for — check your own fit.

What this funds

Money can be used for
Research, R&D, Training, Operating support, Equipment
Who can apply
Small businesses, For-profit companies, Nonprofits, State and local governments, Tribal governments and organizations, Colleges and universities, Other applicants (see eligibility)
Award range
Up to $3,500,000

Questions about this grant

When is the application deadline?
May 28, 2027.
How much funding can an applicant receive?
The largest single award is $3,500,000, and total program funding across the initiative is $33,000,000. The facts do not state a minimum award or the number of awards.
Who can apply for this grant?
Eligible applicants include public and private institutions of higher education, nonprofits with or without 501(c)(3) status, small businesses and other for-profit organizations, state and local governments, federally recognized tribes and tribal organizations, independent school districts, special district governments, and public housing authorities. Foreign organizations and foreign components of U.S. organizations are not eligible, and applications involving foreign subawards or subcontracts will not be considered.
Can a sole proprietor or single-member LLC apply?
The facts do not say. The eligibility list names small businesses and for-profit organizations generally, but sole proprietors and single-member LLCs are not specifically addressed, so check Section III of the NOFO.
Can a nonprofit apply?
Yes. Both nonprofits with 501(c)(3) status and nonprofits without 501(c)(3) status (other than institutions of higher education) are listed as eligible.

Summary

NIH funds multidisciplinary centers (U54) of structural biologists and microbiologists to solve complex biological structures related to prevention, treatment, and cure of HIV and other infectious diseases. Eligible applicants include universities, nonprofits, governments, tribes, and for-profit organizations including small businesses; clinical trials not allowed.

About this grant

The purpose of this notice of funding opportunity (NOFO) is to support multidisciplinary consortia of structural biologists, microbiologists, and associated experts to solve complex biological structures related to the prevention, treatment, and cure of HIV and other infectious diseases. Centers are expected to facilitate new collaborations, leverage shared resources, offer services and resources to the research community, and train the next generation of scientists engaged in structural biology of infectious diseases.

Who can apply

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed. NIH will no longer issue awards (i.e., new, renewal, or non-competing continuation) to domestic or foreign entities that involve foreign subawards/subcontracts. All NIH-funded research involving foreign subawards/subcontracts must be submitted in response to a NOFO that is specifically designated for funded international collaborations. See NIH Grants Policy Statement 16.8 Collaborative International Research Awards.Applications involving foreign subawards/subcontracts submitted in response to this NOFO will be deemed noncompliant and will not be considered for funding. This policy applies to all monetary international collaborations resulting in foreign subawards/subcontracts, however, it does not preclude unfunded international collaborations or foreign components, funding for foreign consultants, or procurement of unique equipment or supplies from foreign vendors.

Topics and uses of funds

Topics

  • Health
  • Science
  • Research

Program contact

National Institutes of HealthBSPDAIDSNOFO@mail.nih.gov301-402-2541

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